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Women under
age 35 who develop breast cancer are more likely to present a
treatment challenge than older premenopausal women, according
to researchers at the European Institute of Oncology and University
of Milan School of Medicine in Italy.
Investigators
evaluated tumor features and stage at diagnosis for 1,427 premenopausal
women referred to surgery from April 1997 to August 2000. A total
of 185 patients (13 percent) were under age 35 (very young) and
1,242 (87 percent) were ages 35 to 50 (less young).
Researchers reported
in the Annals of Oncology that that compared with the less young
women, the very young women had a greater chance of having an endocrine-unresponsive
tumor, and were more likely to have a higher grade tumor, or a extensively
proliferating and vessel invading disease.
No difference
was found between the two groups for pathological stage, tumor
size and number of positive lymph nodes, according to the researchers.
Other
Sources: Annals of Oncology
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