News from Breast Cancer Week of March 3, 2002/ Vol. 2 No. 9

Study: Women Under 35 With Breast Cancer Pose Greater Treatment Challenge

Women under age 35 who develop breast cancer are more likely to present a treatment challenge than older premenopausal women, according to researchers at the European Institute of Oncology and University of Milan School of Medicine in Italy.

Investigators evaluated tumor features and stage at diagnosis for 1,427 premenopausal women referred to surgery from April 1997 to August 2000. A total of 185 patients (13 percent) were under age 35 (very young) and 1,242 (87 percent) were ages 35 to 50 (less young).

Researchers reported in the Annals of Oncology that that compared with the less young women, the very young women had a greater chance of having an endocrine-unresponsive tumor, and were more likely to have a higher grade tumor, or a extensively proliferating and vessel invading disease.

No difference was found between the two groups for pathological stage, tumor size and number of positive lymph nodes, according to the researchers.

Other Sources: Annals of Oncology