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Reducing fat
intake during puberty lowers blood levels of hormones in young
girls that are linked to breast cancer in adult women, according
to researchers at the Fox Chase Cancer Center in Philadelphia.
However, the
researchers said further study will be needed to determine whether
a low-fat diet during adolescence actually results in a reduction
in the risk of the breast cancer later in life.
The study
involved 286 girls aged between 8 and 10, about half of whom were
counseled on following a low-fat diet, in which 28 percent of
calories came from fat and no more than 8 percent from saturated
fat.
Researchers
measured the girls blood sex hormone levels at the start
of the study and over a seven-year period.
Reporting
in the Journal of the National Cancer Institute, the researchers
said that after five years, girls in the low-fat group had lower
levels of specific forms of estrogen linked to breast cancer.
Estradiol
levels were about 30 percent lower and estrone levels were about
20 percent lower, the researchers reported. Levels of progesterone,
which may also increase breast cancer risk, were also lower.
"Although
we do not know if lower hormone levels during adolescence will
influence breast cancer risk in adulthood, adolescence is a time
of rapid growth and maturation of the breasts. Estrogens and progesterones
contribute to the regulation of this process," lead researcher
Dr. Joanne F. Dorgan said.
Other
sources: Journal of the National Cancer Institute
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