|
Researchers
at the U.S. National Cancer Institute have discovered a gene common
to many types of breast cancer that may provide a new point of
attack against the disease.
Scientists
found the gene while looking in test tubes at cells extracted
from different types of breast cancers. They were hoping to find
proteins produced in abundance in breast cancer cells, but absent
in healthy tissues.
A protein
found in cancer but not in normal tissue is seen as a clear sign
of a cancer gene at work.
The researchers
said one gene in particular, known as BASE, caught their attention
because it was present in many types of breast cancer, both local
tumors and those that had spread.
They said
the BASE gene is not the inherited type, but rather is found in
far more common random breast cancers in which cells mutate in
response to an environmental factor.
While the
function of the BASE gene is not totally clear, researchers believe
it is secreted from breast cancer cells into the blood rather
than working solely within cells.
If true, the
researchers said, a simple blood test might ultimately provide
a way of diagnosing many different types of breast cancer.
Other
sources: Proceedings of the National Academy of Sciences
|