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Premenopausal
women who have more than two drinks at a time are at 80 percent
greater risk of developing breast cancer than lighter drinkers
-- even if they both consume the same total amount of alcohol
in a week, according to University of Buffalo researchers.
"In our
study, if a woman had five alcoholic drinks a week, the effect
on breast-cancer risk was greater when the drinks were consumed
on one or two occasions than if she had only one drink on any
one day," said researcher Jo L. Freudenheim.
"We are
not sure why there was this difference," Freudenheim told
a meeting of the Society for Epidemiologic Researchers. "But
it could be that the higher alcohol load at one time taxes the
body's ability to handle alcohol's potentially toxic effects."
The University
of Buffalo study involved 1,120 women with confirmed breast cancer
and 2,240 healthy controls matched to those with cancer by age
and race.
Freudenheim
said that while having more than two drinks at a time, also significantly
increased breast-cancer risk for premenopausal women, it did not
appear to increase risk of breast cancer for postmenopausal women.
But Saverio
Stranges, a research instructor at the University of Buffalo,
said the results clearly suggest that "if you drink, drink
in moderation and in a healthy way, with food, and spread the
consumption over a longer period of time, rather than in a short
period, such as a weekend."
Other
Sources: University of Buffalo
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