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Women diagnosed
with ductal carcinoma in situ (DCIS) -- a precancer that occurs
when cells in the lining of the milk ducts in the breast show
cancerous changes -- can significantly lower their risk of a recurrence
of breast cancer by having radiation therapy, according to researchers.
In a study
of 1,700 women in Britain, Australia and New Zealand, radiation
therapy cut the risk of a recurrence of DCIS in the same breast
by 60 percent, and the risk of invasive cancer by more than 50
percent, the researchers reported in the journal The Lancet.
All of the
women in the trial had surgery and subsequently received either
radiotherapy and tamoxifen or both, or had no further treatment.
Advances in
breast screening have led to an increase in the number of women
diagnosed with DCIS, a precancer that occurs when cells in the
lining of the milk ducts in the breast show cancerous changes.
While a mastectomy may be necessary if the DCIS is extensive,
more commonly it is treated by removing the affected area followed
by radiation therapy.
The researchers
said the results of the study supported findings from two earlier
studies that showed the benefits of radiation therapy for DCIS
patients.
Other
Sources: The Lancet
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