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British researchers
report that blocking a "Pied Piper" protein that attracts
breast cancer cells could help prevent the spread of the disease
to other parts of the body.
Reporting
in the Journal of Cell Biology, the researchers said they found
that that breast cancer cells are attracted to a naturally occurring
protein called uPA.
When the action
of this protein was blocked with certain antibodies, the cells
stopped moving.
The importance
of this discovery lies in the fact that when malignant cells are
confined to the breast, the illness is far less likely to be fatal.
"Preventing
the spread of breast cancer is key to removing its fatality,"
said Professor Clare Isacke of the Breakthrough Breast Cancer
Research Centre in London.
"Now
that we have a crucial understanding of how cells move in particular
directions, we have the potential to identify new methods to diagnose,
prevent and treat the spread of breast cancers," Isacke said.
Other
Sources: Journal of Cell Biology
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