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Breast cancer
in women over the age of 80 is frequently undertreated, resulting
in a significantly higher death rate, according to Swiss researchers.
Dr. Christine
Bouchardy from the Geneva Cancer Registry used data from the registry
to evaluate the effect of various courses of treatment on 407
elderly women diagnosed with breast cancer.
Twelve percent
of the women received no treatment for their breast cancer, the
researchers found, while 32 percent received tamoxifen as the
sole therapy. Seven percent had a lumpectomy with no radiation
therapy, 14 percent had a lumpectomy plus radiation therapy, the
remainder had a mastectomies.
"In this
study, only 47 percent of elderly women received standard treatment
compared with 91 percent of women aged 50 to 79 years recorded
in the registry for the same period," the researchers reported
in the Journal of Clinical Oncology.
As a result,
five-year survival was 90 percent for women who had lumpectomies
plus other treatment, but only 51 percent for women treated with
tamoxifen alone and 46 percent for women who had no treatment.
"Breast
cancer treatment in elderly women remains a complex problem for
clinicians," the researchers said. "There is disagreement
about the optimum treatment.
"Treatment
needs to be adapted to the patient's general health status and
conditions, but has to offer the best chance of cure, regardless
of age," the researchers concluded.
Other
Sources: Journal of Clinical Oncology
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