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When a well-trained physician performs a fine needle aspiration
of the breast, the diagnostic procedure is highly accurate and
cost-effective and could replace a large number of surgical biopsies,
according to researchers at the University of California, San
Francisco and the University of Vermont.
However,
when inadequately trained physicians perform fine needle aspiration
of the breast, the procedure may be misleading and potentially
harmful, according to a study published in Cancer Cytopathology.
Researchers
designed a study to examine the effects of training doctors in
the sampling technique of fine needle aspirations from palpable
breast masses.
Aspirations
were performed by 729 formally trained doctors who had previously
performed 150 aspirations under supervision and another 100 during
the year. Doctors
who had received no formal training and had performed an average
of only 2 aspirations during the year aspirated 314 specimens.
Specimens
were evaluated for cellularity and type of material present to
establish accuracy of diagnosis, and the rate of surgical intervention.
All
cases were matched with the Northern California Cancer Registry
and followed up for 2 years. Aspiration
specimens were correlated with histologic specimens when they
were available.
The formally
trained doctors missed 2 percent of malignancies compared with
25 percent missed by the untrained physicians, reported the researchers.
Other
Sources: Cancer Cytopathology
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